CAMAF Member Option Guides & Info

Information provided by Ecsponent Biotech, (www.ecsbio.com) on behalf of: This is for information and educational purposes only, and should not be construed as healthcare advice. Please discuss with your healthcare professional. A full list of references is available on the website and at our offices. Data on file. DOC 9.0.1.105.9.SA V1 Effective date: 5 May 2017 Speak to your doctor or midwife about the importance of collecting enough cord blood. COLLECTING CORD BLOOD IS A SAFE, EASY AND PAINLESS PROCEDURE THAT CAN SUCCESSFULLY BE COMBINED WITH DELAYED CORD CLAMPING. The placenta and umbilical cord hold enough blood to allow delaying the cord clamping by 1 – 3 minutes (the recommended time given by the World Health Organization) and still have enough for a successful cord blood collection. Chances of a successful collection will naturally increase by combing in+ex utero collection. The most important consideration is collecting enough cord blood because in general, there is a correlation between the volume of cord blood collected and the number of stem cells in a collection. Combining in- and ex-utero collection is the best-practice solution to collect enough cord blood. Combining these methods is particularly useful when the in-utero volume is low, for example due to delayed cord clamping. Stage 2 Labour Cord blood collection takes place after birth and only once the umbilical cord has been clamped and cut. It is a painless procedure that poses no risk to mother or baby. In-utero collection With in-utero collection, the cord blood is collected immediately after the umbilical cord has been cut and before the expulsion of the placenta. This extraction mode requires about 10 minutes and is faster because uterine contractions allows cord blood to flow more easily. Ex-utero collection Ex-utero collection takes place after the expulsion of the placenta and takes about 25 minutes to complete. Other benefits of combining these collection methods include: • There is a significantly higher total nucleated cell counts (TNC) in the in- & ex-utero collection vs. in- utero collection. • There is no statistically significant difference in the microbial contamination rate in in-utero vs. in- & ex- utero collection, however it is lower in the ex-utero collection compared to either the in-utero or ex utero collections. • In- and-ex utero collection of umbilical cord blood for banking is safe and results in significantly higher TNCs than either technique alone. Improving the collection to ensure the best possible outcome

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