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Ecsponent Biotech

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Information provided by Ecsponent Biotech, (www.ecsbio.com) on behalf of: This is for information and educational purposes only, and should not be construed as healthcare advice. Please discuss with your healthcare professional. A full list of references is available on the website and at our offices. Data on file. DOC 9.0.1.105.9.SA V1 Effective date: 5 May 2017 What is the difference between umbilical cord blood and cord tissue stem cells How is it collected After birth the umbilical cord is clamped and cut before the baby is taken away for care. The blood is collected from the umbilical cord in a quick, painless and non-invasive procedure. What type of stem cells it contains Blood stem cells/ Haematopoietic stem cells (HSCs) in umbilical cord blood are blood-forming stem cells that can differentiate into red blood cells, white blood cells and platelets. What is it used for Blood-forming stem cells are used to treat bone marrow failure, blood cancer and other blood disorders. First used Cord blood stem cells were 1 st successfully transplanted in 1988, and now it is used to treat over 80 blood-related diseases. Evolving medicine In addition to the current treatments, FDA-regulated clinical trails are underway to study ways in which cord blood stem cells can be used as treatment for: • cerebral palsy • traumatic brain injury • acquired hearing loss • juvenile diabetes CORD BLOOD How is it collected A 20-25cm segment of the umbilical cord is collected after birth. What type of stem cells it contains The stem cells found in the umbilical cord tissue (Wharton's jelly) is called mesenchymal stem cells (MSC). The umbilical cord vein and arteries contain endothelial stem cells and the umbilical cord lining contains both mesenchymal stem cells and epithelial stem cells. What is it used for MSCs are able to differentiate into cartilage cells, muscle cells, bone cells, nerve cells, etc. Future treatments may include Alzheimer's, liver and heart failure, bone regeneration, HIV, Type 1 diabetes, and more. First used Clinical trials using MSCs started in 1995, with more than 200 trials currently underway. Evolving medicine Cord tissue MSC are being evaluated in laboratory studies and clinical trials to treat: • heart disease • spinal cord injury • cartilage injury • liver disease CORD TISSUE

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