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Ecsponent Biotech

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Information provided by Ecsponent Biotech, (www.ecsbio.com) on behalf of: This is for information and educational purposes only, and should not be construed as healthcare advice. Please discuss with your healthcare professional. A full list of references is available on the website and at our offices. Data on file. DOC 9.0.1.105.9.SA V1 Effective date: 5 May 2017 What are blood stem cell transplants? American doctor E. Donnall Thomas did the first successful bone marrow transplant to cure leukaemia. New York, 1956 Blood stem cell transplantation, using stem blood cells from sources such as bone marrow, has been performed for MORE THAN 50 YEARS, with more than 1 MILLION BLOOD STEM CELL TRANSPLANTS across the world playing an important role in the treatment of bone marrow failures, blood cancers, blood disorders, metabolic diseases, immune deficiencies and autoimmune diseases. Why may a bone marrow transplant (also called a blood stem cell transplant) be needed? To treat and/or cure certain types of blood related disease, for example to: • replace diseased bone marrow with healthy bone marrow to treat/cure patients with e.g. blood cancer • replace non-functioning bone marrow with healthy functioning bone marrow in patients with e.g. acquired bone marrow failure. • regenerate a healthy immune system in patients with e.g. immune deficiencies, auto-immune disease. • replace bone marrow with genetically healthy functioning bone marrow in patients with inherited blood related diseases. What are your chances of finding a blood stem cell donor in SA? Bone marrow transplants require a perfect tissue match in most cases THERE IS NO PUBLIC UMBILICAL CORD BLOOD BANK IN SOUTH AFRICA. Depending in a person's tissue type, the chance of finding a bone marrow donor may be less than 1 in a 100 000 of patients in need of a blood stem cell transplant won't have a sibling donor 70% 1 in a 100 000 healthy donors registered on the SABMR 75 000

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